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KMID : 0615720030200020184
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Jouranl of Korean Acupuncture and Moxibustion society
2003 Volume.20 No. 2 p.184 ~ p.194
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Scavenging Effect on NO, DPPH and Inhibitory Effect on IL-4 in Astragali Radix Herbal-Acupuncture Solution
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Abstract
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Objective : This study was designed fo find out whether Astragali Rdix Herbal-Acupuncture Solution(ARHA) can scavenge NO, DPPH and IL-4 or not Astragali Radix has been clinically used to reforce the depression of immune reponse etc. in Oriental Medicine.
Methods : Free radical metabolism seems to occupy s remarkably common position in the mechanisms of ageing and ageing related disease. Oxidative damage to DNA, lipids, proteins and other molecules may contribute to the development of cancer. cardiovascular disease and possibly neurodegenerative disease. The effests of ARHA on NO, DPPH and IL-4 were measured.
Results : The followings are the summary of the result;
① There is a significant scavenging effect of ARHA on NO in l, 10㎎/㎖ group in after 24hrs.
② There is no significant scavenging effect of ARHA on DPPH.
③ There is a significant scavenging effect oa ARHA on IL-4 in l, 10,100㎍/㎖ group.
Conclusions : Teese results suggest that ARHA has significant scavenging effect on NO, IL-4 and nat on DPPH. This study shows that ARHA can be used for ageing related disease and further studies are required to investigate the antiozidative effects of it.
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KEYWORD
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